OLR1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human OLR1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human OLR1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human OLR1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — OLR1
Entrez GeneID
4973GeneBank Accession#
OLR1Gene Name
OLR1
Gene Alias
CLEC8A, LOX1, SCARE1
Gene Description
oxidized low density lipoprotein (lectin-like) receptor 1
Omim ID
602601Gene Ontology
HyperlinkGene Summary
This gene encodes a receptor protein which belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternative transcript variants have been described but their full-length sequence has not been determined. [provided by RefSeq
Other Designations
lectin-type oxidized LDL receptor 1|oxidised low density lipoprotein (lectin-like) receptor 1|scavenger receptor class E, member 1
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