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OGG1 (Human) IP-WB Antibody Pair

  • Catalog # : H00004968-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00004968-PW1
    Immunoprecipitation of OGG1 transfected lysate using rabbit polyclonal anti-OGG1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-OGG1.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-OGG1 (300 ul)
    2. Antibody pair for WB: mouse polyclonal anti-OGG1 (50 ul)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 4968
  • Gene Name:
  • OGG1
  • Gene Alias:
  • Gene Description:
  • 8-oxoguanine DNA glycosylase
  • Gene Summary:
  • This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq
  • Other Designations:
  • 8-hydroxyguanine DNA glycosylase,OTTHUMP00000122619
  • Gene Pathway
  • Related Disease
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