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OGDH rabbit monoclonal antibody

  • Catalog # : H00004967-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human OGDH peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human OGDH is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human OGDH peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4967
  • GeneBank Accession#:
  • OGDH
  • Gene Name:
  • OGDH
  • Gene Alias:
  • AKGDH,E1k,OGDC
  • Gene Description:
  • oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
  • Gene Summary:
  • This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms
  • Other Designations:
  • 2-oxoglutarate dehydrogenase,H_DJ0691F11_gi16307008.sp_cds.1,oxoglutarate decarboxylase',oxoglutarate dehydrogenase (lipoamide),oxoglutarate dehydrogenase (succinyl-transferring)
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