OCLN (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human OCLN full-length ORF ( AAH29886, 1 a.a. - 522 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSSRPLESPPPYRPDEFKPNHYAPSNDIYGGEMHVRPMLSQPAYSFYPEDEILHFYKWTSPPGVIRILSMLIIVMCIAIFACVASTLAWDRGYGTSLLGGSVGYPYGGSGFGSYGSGYGYGYGYGYGYGGYTDPRAAKGFMLAMAAFCFIAALVIFVTSVIRSEMSRTRRYYLSVIIVSAILGIMVFIATIVYIMGVNPTAQSSGSLYGSQIYALCNQFYTPAATGLYVDQYSYHYCVVDPQEAIAIVLGFMIIVAFALIIFFAVKTRRKMDRYDKSNILWDKEHIYDEQPPNVEEWVKNVSAGTQDVPSPPSDYVERVDSPMAYSSNGKVNDKRFYPESSYKSTPVPEVVQELPLTSPVDDFRQPRYSSGGNFETPSKRAPAKGRAGRSKRTEQDHYETDYTTGGESCDELEEDWIREYPPITSDQQRQLYKRNFDTGLQEYKSLQSELDEINKELSRLDKELDDYREESEEYMAAADEYNRLKQVKGSADYKSKKNHCKQLKSKLSHIKKMVGDYDRQKT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
82.94
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — OCLN
Entrez GeneID
4950GeneBank Accession#
BC029886Protein Accession#
AAH29886Gene Name
OCLN
Gene Alias
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Gene Description
occludin
Omim ID
602876Gene Ontology
HyperlinkGene Summary
This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described. [provided by RefSeq
Other Designations
tight junction protein occludin TM4 minus
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Pathway
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Publication Reference
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Is later-life depression a risk factor for Alzheimer's disease or a prodromal symptom: a study using post-mortem human brain tissue?
Lindsey I Sinclair, Asher Mohr, Mizuki Morisaki, Martin Edmondson, Selina Chan, A Bone-Connaughton, Gustavo Turecki, Seth Love.
Alzheimer's Research & Therapy 2023 Sep; 15(1):153.
Application：S-ELISA, Human, Human cerebral cortex.
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Helicobacter pylori Employs a Unique Basolateral Type IV Secretion Mechanism for CagA Delivery.
Tegtmeyer N, Wessler S, Necchi V, Rohde M, Harrer A, Rau TT, Asche CI, Boehm M, Loessner H, Figueiredo C, Naumann M, Palmisano R, Solcia E, Ricci V, Backert S.
Cell Host & Microbe 2017 Oct; 22(4):552.
Application：Func, HtrA.
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Kiwifruit cysteine protease actinidin compromises the intestinal barrier by disrupting tight junctions.
Grozdanovic MM, Čavić M, Nešić A, Andjelković U, Akbari P, Smit JJ, Gavrović-Jankulović M.
Biochimica et Biophysica Acta 2016 Mar; 1860(3):516.
Application：Added, Recombinant protein.
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Is later-life depression a risk factor for Alzheimer's disease or a prodromal symptom: a study using post-mortem human brain tissue?
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