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OAS1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00004938-T03
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-OAS1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 40.04
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-OAS1 antibody (H00004938-D03P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00004938-T03
    OAS1 transfected lysate.
    Western Blot
    QC Testing of H00004938-T03
    Lane 1: OAS1 transfected lysate ( 40.04 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 4938
  • Gene Name:
  • OAS1
  • Gene Alias:
  • IFI-4,OIAS,OIASI
  • Gene Description:
  • 2',5'-oligoadenylate synthetase 1, 40/46kDa
  • Gene Summary:
  • This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • (2'-5') oligoadenylate synthetase 1,2',5'-oligo A synthetase 1,2',5'-oligoadenylate synthetase 1,2',5'-oligoadenylate synthetase 1 (40-46 kD),2'-5' oligoadenylate synthetase 1 p48 isoform,2'-5' oligoadenylate synthetase 1 p52 isoform,2'-5'-oligoisoadenyla
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