SLC11A2 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human SLC11A2 partial ORF ( NP_000608, 1 a.a. - 65 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MVLGPEQKMSDDSVSGDHGESASLGNINPAYSNPSLSQSPGDSEEYFATYFNEKISIPEEEYSCF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.89
Interspecies Antigen Sequence
Mouse (75); Rat (75)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SLC11A2
Entrez GeneID
4891GeneBank Accession#
NM_000617Protein Accession#
NP_000608Gene Name
SLC11A2
Gene Alias
DCT1, DMT1, FLJ37416, NRAMP2
Gene Description
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Gene Ontology
HyperlinkGene Summary
The SLC11A2 gene encodes a divalent metal transporter (DMT1), which carries iron, manganese, cobalt, nickel, cadmium, lead, copper, and zinc. DMT1 participates in cellular iron absorption at the luminal surface of the duodenum as well as in other areas of the body (Hubert and Hentze, 2002 [PubMed 12209011]; Ludwiczek et al., 2007 [PubMed 17293870]).[supplied by OMIM
Other Designations
natural resistance-associated macrophage protein 2
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Interactome
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Pathway
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