NPTX2 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-NPTX2 full-length
Host
Human
Theoretical MW (kDa)
47
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-NPTX2 antibody (H00004885-B01) by Western Blots.
SDS-PAGE Gel
NPTX2 transfected lysate.
Western Blot
Lane 1: NPTX2 transfected lysate ( 47 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — NPTX2
Entrez GeneID
4885GeneBank Accession#
NM_002523Protein Accession#
NP_002514Gene Name
NPTX2
Gene Alias
NARP, NP-II, NP2
Gene Description
neuronal pentraxin II
Omim ID
600750Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq
Other Designations
apexin|neuronal activity-regulated pentaxin|pentraxin II
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Interactome
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Disease
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