NPTX2 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96%); Rat (95%)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of NPTX2 transfected lysate using rabbit polyclonal anti-NPTX2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-NPTX2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-NPTX2 (300 ul)
2. Antibody pair for WB: mouse polyclonal anti-NPTX2 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — NPTX2
Entrez GeneID
4885Gene Name
NPTX2
Gene Alias
NARP, NP-II, NP2
Gene Description
neuronal pentraxin II
Omim ID
600750Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq
Other Designations
apexin|neuronal activity-regulated pentaxin|pentraxin II
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Interactome
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Disease
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