NPR2 DNAxPab
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of NPR2 expression in transfected 293T cell line by NPR2 DNAxPab polyclonal antibody.
Lane 1: NPR2 transfected lysate(68.97 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human NPR2 DNA using DNAx™ Immune technology.
Technology
Immunogen
NPR2 (AAH96341.1, 23 a.a. ~ 457 a.a) partial-length human DNA
Sequence
RNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRALPVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLLTAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWWTGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NPR2 expression in transfected 293T cell line by NPR2 DNAxPab polyclonal antibody.
Lane 1: NPR2 transfected lysate(68.97 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — NPR2
Entrez GeneID
4882GeneBank Accession#
BC096341.1Protein Accession#
AAH96341.1Gene Name
NPR2
Gene Alias
AMDM, ANPRB, GUC2B, GUCY2B, NPRB, NPRBi
Gene Description
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
Gene Ontology
HyperlinkGene Summary
This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq
Other Designations
OTTHUMP00000021345|OTTHUMP00000045390|atrial natriuretic peptide B-type receptor|guanylate cyclase B|natriuretic peptide receptor B
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Interactome
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Pathway
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Disease
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