NPPA (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human NPPA full-length ORF ( AAH05893, 1 a.a. - 153 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSSFSTTTVSFLLLLAFQLLGQTRANPMYNAVSNADLMDFKNLLDHLEEKMPLEDEVVPPQVLSEPNEEAGAALSPLPEVPPWTGEVSPAQRDGGALGRGPWDSSDRSALLKSKLRALLTAPRSLRRSSCFGGRMDGIGAQSGLGCNSFRYRR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
42.57
Interspecies Antigen Sequence
Mouse (80); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NPPA
Entrez GeneID
4878GeneBank Accession#
BC005893Protein Accession#
AAH05893Gene Name
NPPA
Gene Alias
ANF, ANP, ATFB6, CDD-ANF, PND
Gene Description
natriuretic peptide precursor A
Omim ID
108780Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq
Other Designations
OTTHUMP00000002504|OTTHUMP00000044485|atrial natriuretic peptide|natriuretic peptide precursor A variant 2|pronatriodilatin
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Interactome
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Disease
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