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Last updated: 2016/12/11

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NPPA rabbit monoclonal antibody

  • Catalog # : H00004878-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human NPPA peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human NPPA is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human NPPA peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4878
  • GeneBank Accession#:
  • NPPA
  • Gene Name:
  • NPPA
  • Gene Alias:
  • ANF,ANP,ATFB6,CDD-ANF,PND
  • Gene Description:
  • natriuretic peptide precursor A
  • Gene Summary:
  • The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000002504,OTTHUMP00000044485,atrial natriuretic peptide,natriuretic peptide precursor A variant 2,pronatriodilatin
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