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NPHP1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00004867-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-NPHP1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 13.42
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-NPHP1 antibody (H00004867-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00004867-T01
    NPHP1 transfected lysate.
    Western Blot
    QC Testing of H00004867-T01
    Lane 1: NPHP1 transfected lysate ( 13.42 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 4867
  • Gene Name:
  • NPHP1
  • Gene Alias:
  • FLJ97602,JBTS4,NPH1,SLSN1
  • Gene Description:
  • nephronophthisis 1 (juvenile)
  • Gene Summary:
  • This gene encodes a protein with src homology domain 3 (SH3) patterns. This protein interacts with Crk-associated substrate, and it appears to function in the control of cell division, as well as in cell-cell and cell-matrix adhesion signaling, likely as part of a multifunctional complex localized in actin- and microtubule-based structures. Mutations in this gene cause familial juvenile nephronophthisis type 1, a kidney disorder involving both tubules and glomeruli. Defects in this gene are also associated with Senior-Loken syndrome type 1, also referred to as juvenile nephronophthisis with Leber amaurosis, which is characterized by kidney and eye disease, and with Joubert syndrome type 4, which is characterized by cerebellar ataxia, oculomotor apraxia, psychomotor delay and neonatal breathing abnormalities, sometimes including retinal dystrophy and renal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • nephrocystin-1
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