NOS2 monoclonal antibody (M11), clone 2G4
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant NOS2.
Immunogen
NOS2 (NP_000616, 685 a.a. ~ 794 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DVRGKQHIQIPKLYTSNVTWDPHHYRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQPALVQGILERVVDG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72); Rat (71)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NOS2 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — NOS2
Entrez GeneID
4843GeneBank Accession#
NM_000625Protein Accession#
NP_000616Gene Name
NOS2
Gene Alias
HEP-NOS, INOS, NOS, NOS2A
Gene Description
nitric oxide synthase 2, inducible
Gene Ontology
HyperlinkGene Summary
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq
Other Designations
NOS, type II|nitric oxide synthase 2A|nitric oxide synthase 2A (inducible, hepatocytes)|nitric oxide synthase, macrophage
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Interactomes
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Pathways
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Diseases
- Acute Disease
- Adenocarcinoma
- Albuminuria
- Alzheimer disease
- Anemia
- Angina
- Angina Pectoris
- Arthritis
- Asthma
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