NMT1 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human NMT1 full-length ORF ( NP_066565.1, 1 a.a. - 496 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MADESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKKQKKKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
83.2
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NMT1
Entrez GeneID
4836GeneBank Accession#
NM_021079.3Protein Accession#
NP_066565.1Gene Name
NMT1
Gene Alias
NMT
Gene Description
N-myristoyltransferase 1
Omim ID
160993Gene Ontology
HyperlinkGene Summary
Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase (NMT; EC 2.3.1.97) catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1; MIM 139311) (Duronio et al., 1992 [PubMed 1570339]).[supplied by OMIM
Other Designations
alternative, short form NMT-S|long form, NMT-L|myristoyl-CoA:protein N-myristoyltransferase
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Interactome
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Disease
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Publication Reference
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Inhibition of N-myristoyltransferase1 affects dengue virus replication.
Suwanmanee S, Mahakhunkijcharoen Y, Ampawong S, Leaungwutiwong P, Missé D, Luplertlop N.
Microbiologyopen 2019 Mar; e00831.
Application：Func, WB, Human, Induced dendritic cells, Recombinant protein.
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Inhibition of N-myristoyltransferase1 affects dengue virus replication.
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