Western blot analysis of NME2 over-expressed 293 cell line, cotransfected with NME2 Validated Chimera RNAi ( Cat # H00004831-R11V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with NME2 monoclonal antibody (M01), clone 4B7-3F12 (Cat # H00004831-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) which encode a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq
NDP kinase B,OTTHUMP00000174727,OTTHUMP00000174728,OTTHUMP00000174774,OTTHUMP00000174775,OTTHUMP00000174776,c-myc transcription factor,non-metastatic cells 2, protein (NM23) expressed in