NKX6-1 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human NKX6-1 full-length ORF ( AAI60030.1, 1 a.a. - 367 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLAVGAMEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGGGGGLLLHASEPESSS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
66.77
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NKX6-1
Entrez GeneID
4825GeneBank Accession#
BC160030.1Protein Accession#
AAI60030.1Gene Name
NKX6-1
Gene Alias
NKX6.1, NKX6A
Gene Description
NK6 homeobox 1
Omim ID
602563Gene Ontology
HyperlinkGene Summary
In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM
Other Designations
NK homeo box, family 6, member A|NK homeobox, family 6, A|NK6 transcription factor homolog A|NK6 transcription factor related, locus 1
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Interactome
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Pathway
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Disease
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