NKX6-1 monoclonal antibody (M02), clone 1A7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant NKX6-1.
Immunogen
NKX6-1 (NP_006159, 191 a.a. ~ 275 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGM*
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.46 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — NKX6-1
Entrez GeneID
4825GeneBank Accession#
NM_006168Protein Accession#
NP_006159Gene Name
NKX6-1
Gene Alias
NKX6.1, NKX6A
Gene Description
NK6 homeobox 1
Omim ID
602563Gene Ontology
HyperlinkGene Summary
In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM
Other Designations
NK homeo box, family 6, member A|NK homeobox, family 6, A|NK6 transcription factor homolog A|NK6 transcription factor related, locus 1
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Interactome
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Pathway
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Disease
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