NKX3-1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human NKX3-1 partial ORF ( NP_006158, 100 a.a. - 209 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRAS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NKX3-1
Entrez GeneID
4824GeneBank Accession#
NM_006167Protein Accession#
NP_006158Gene Name
NKX3-1
Gene Alias
BAPX2, NKX3, NKX3.1, NKX3A
Gene Description
NK3 homeobox 1
Omim ID
602041Gene Ontology
HyperlinkGene Summary
The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM
Other Designations
NK homeobox, family 3, A|NK3 transcription factor homolog A|NK3 transcription factor related, locus 1|OTTHUMP00000123534
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