NKX3-1 monoclonal antibody (M01), clone 3H6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NKX3-1.
Immunogen
NKX3-1 (NP_006158, 100 a.a. ~ 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GSYLLDSENTSGALPRLPQTPKQPQKRSRAAFSHTQVIELERKFSHQKYLSAPERAHLAKNLKLTETQVKIWFQNRRYKTKRKQLSSELGDLEKHSSLPALKEEAFSRAS
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
NKX3-1 monoclonal antibody (M01), clone 3H6. Western Blot analysis of NKX3-1 expression in human colon.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NKX3-1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — NKX3-1
Entrez GeneID
4824GeneBank Accession#
NM_006167Protein Accession#
NP_006158Gene Name
NKX3-1
Gene Alias
BAPX2, NKX3, NKX3.1, NKX3A
Gene Description
NK3 homeobox 1
Omim ID
602041Gene Ontology
HyperlinkGene Summary
The homeodomain-containing transcription factor NKX3-1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3-1 protein expression is a common finding in human prostate carcinomas and prostatic intraepithelial neoplasia.[supplied by OMIM
Other Designations
NK homeobox, family 3, A|NK3 transcription factor homolog A|NK3 transcription factor related, locus 1|OTTHUMP00000123534
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