NFKBIL2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human NFKBIL2 partial ORF ( NP_038460, 1 a.a. - 97 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MRTRLYLNLGLTFESLQQTALCNDYFRKSIFLAEQNHLYEDLFRARYNLGTIHWRAGQHSQAMRCLEGARECAHTMRKRFMESECCVVIAQVLQDLG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.41
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NFKBIL2
Entrez GeneID
4796GeneBank Accession#
NM_013432Protein Accession#
NP_038460Gene Name
NFKBIL2
Gene Alias
FLJ40087, IKBR
Gene Description
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2
Omim ID
604546Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus. [provided by RefSeq
Other Designations
I-kappa-B-related protein|NF-kappa-B inhibitor-like protein 2
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Interactome
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Disease
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