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NFKBIB (Human) Matched Antibody Pair

  • Catalog # : H00004793-AP21
  • Visit Frequency :
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  • Specification
  • Product Description:
  • This antibody pair set comes with matched antibody pair to detect and quantify protein level of human NFKBIB.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Standard curve using recombinant protein ( H00004793-P01 ) as an analyte.

    QC Testing of H00004793-AP21
    Sandwich ELISA detection sensitivity ranging from 0.3 ng/ml to 100 ng/ml.
  • Supplied Product:
  • Antibody pair set content:
    1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-NFKBIB (100 ug)
    2. Detection antibody: mouse polyclonal anti-NFKBIB (40 ul)
    *Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • ELISA Pair (Recombinant protein)
  • Gene Information
  • Entrez GeneID:
  • 4793
  • Gene Name:
  • Gene Alias:
  • Gene Description:
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
  • Gene Summary:
  • NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine).[supplied by OMIM
  • Other Designations:
  • -
  • Interactome
  • Interactome
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