NFATC3 monoclonal antibody (M02), clone 3A12
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NFATC3.
Immunogen
NFATC3 (NP_775188, 70 a.a. ~ 149 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (86)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to NFATC3 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1.5 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NFATC3 is approximately 10ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to NFATC3 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — NFATC3
Entrez GeneID
4775GeneBank Accession#
NM_173165Protein Accession#
NP_775188Gene Name
NFATC3
Gene Alias
NFAT4, NFATX
Gene Description
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
Omim ID
602698Gene Ontology
HyperlinkGene Summary
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
T cell transcription factor NFAT4|nuclear factor of activated T-cells c3 isoform IE-Xa|nuclear factor of activated T-cells, cytoplasmic 3
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Interactome
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Disease
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