NFATC2 monoclonal antibody (M01A), clone 2A4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NFATC2.
Immunogen
NFATC2 (NP_036472, 812 a.a. ~ 921 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
HYSPTNQQLRCGSHQEFQHIMYCENFAPGTTRPGPPPVSQGQRLSPGSYPTVIQQQNATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNLDQTYLDDELIDTRLSWIQNIL
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — NFATC2
Entrez GeneID
4773GeneBank Accession#
NM_012340Protein Accession#
NP_036472Gene Name
NFATC2
Gene Alias
KIAA0611, NFAT1, NFATP
Gene Description
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
Omim ID
600490Gene Ontology
HyperlinkGene Summary
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
NFAT pre-existing subunit|NFAT transcription complex, preexisting component|OTTHUMP00000031291|T cell transcription factor NFAT1|nuclear factor of activated T-cells, cytoplasmic 2|nuclear factor of activated T-cells, preexisting component|preexisting nucl
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Interactome
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Disease
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