Products

Western Blot (Recombinant protein)

ELISA

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

NFATC2

Gene Alias

KIAA0611, NFAT1, NFATP

Gene Description

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

Omim ID

Gene Ontology

Gene Summary

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq

Other Designations

NFAT pre-existing subunit|NFAT transcription complex, preexisting component|OTTHUMP00000031291|T cell transcription factor NFAT1|nuclear factor of activated T-cells, cytoplasmic 2|nuclear factor of activated T-cells, preexisting component|preexisting nucl