NFATC1 polyclonal antibody (A01)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant NFATC1.
Immunogen
NFATC1 (NP_006153, 701 a.a. ~ 810 a.a) partial recombinant protein with GST tag.
Sequence
IKTEPTDDYEPAPTCGPVSQGLSPLPRPYYSQQLAMPPDPSSCLVAGFPPCPQRSTLMPAAPGVSPKLHDLSPAAYTKGVASPGHCHLGLPQPAGEAPAVQDVPRPVATH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (75); Rat (73)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Recombinant protein)
ELISA
-
Gene Info — NFATC1
Entrez GeneID
4772GeneBank Accession#
NM_006162Protein Accession#
NP_006153Gene Name
NFATC1
Gene Alias
MGC138448, NF-ATC, NFAT2, NFATc
Gene Description
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
Omim ID
600489Gene Ontology
HyperlinkGene Summary
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes. [provided by RefSeq
Other Designations
NFAT transcription complex cytosolic component|nuclear factor of activated T-cells, cytosolic component 1
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
PROSER2 is a poor prognostic biomarker for patients with osteosarcoma and promotes proliferation, migration and invasion of osteosarcoma cells.
Zhengjiang Li, Yan Zhang, Yongkui Li, Shuxing Xing, Shunqiang Li, Jing Lyu, Zhaonan Ban.
Experimental and Therapeutic Medicine 2022 Nov; 24(6):750.
Application:WB-Tr, Human, MG63 cells.
-
PROSER2 is a poor prognostic biomarker for patients with osteosarcoma and promotes proliferation, migration and invasion of osteosarcoma cells.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com