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NEU1 Pre-design Chimera RNAi

  • Catalog # : H00004758-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens sialidase 1 (lysosomal sialidase) (NEU1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000434
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 4758
  • Gene Name:
  • NEU1
  • Gene Alias:
  • FLJ93471,NANH,NEU,SIAL1
  • Gene Description:
  • sialidase 1 (lysosomal sialidase)
  • Gene Summary:
  • The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein'). Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq
  • Other Designations:
  • G9 sialidase,N-acetyl-alpha-neuraminidase 1,OTTHUMP00000029419,acetylneuraminyl hydrolase,exo-alpha-sialidase,lysosomal sialidase,neuraminidase
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