NELL2 monoclonal antibody (M03), clone 2D11
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NELL2.
Immunogen
NELL2 (NP_006150.1, 301 a.a. ~ 400 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IQCETLICPNPDCPLKSALAYVDGKCCKECKSICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCCKVCKGYDF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (87)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NELL2 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — NELL2
Entrez GeneID
4753GeneBank Accession#
NM_006159Protein Accession#
NP_006150.1Gene Name
NELL2
Gene Alias
NRP2
Gene Description
NEL-like 2 (chicken)
Omim ID
602320Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq
Other Designations
nel-like 2|neural epidermal growth factor-like 2
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Interactome
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Disease
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