NEFL MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Cell lysate)
NEFL MaxPab rabbit polyclonal antibody. Western Blot analysis of NEFL expression in Hela S3 NE.
Western Blot (Transfected lysate)
Western Blot analysis of NEFL expression in transfected 293T cell line (H00004747-T01) by NEFL MaxPab polyclonal antibody.
Lane 1: NEFL transfected lysate(61.5 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of NEFL transfected lysate using anti-NEFL MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with NEFL purified MaxPab mouse polyclonal antibody (B01P) (H00004747-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human NEFL protein.
Immunogen
NEFL (NP_006149.2, 1 a.a. ~ 543 a.a) full-length human protein.
Sequence
MSSFSYEPYYSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQAQIQYAQISVEMDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYGGLQTSSYLMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKVEGAGEEQAAKKKD
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
NEFL MaxPab rabbit polyclonal antibody. Western Blot analysis of NEFL expression in Hela S3 NE.Western Blot (Transfected lysate)
Western Blot analysis of NEFL expression in transfected 293T cell line (H00004747-T01) by NEFL MaxPab polyclonal antibody.
Lane 1: NEFL transfected lysate(61.5 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of NEFL transfected lysate using anti-NEFL MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with NEFL purified MaxPab mouse polyclonal antibody (B01P) (H00004747-B01P). -
Gene Info — NEFL
Entrez GeneID
4747GeneBank Accession#
NM_006158.2Protein Accession#
NP_006149.2Gene Name
NEFL
Gene Alias
CMT1F, CMT2E, FLJ53642, NF-L, NF68, NFL
Gene Description
neurofilament, light polypeptide
Gene Ontology
HyperlinkGene Summary
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq
Other Designations
light molecular weight neurofilament protein|neurofilament protein, light chain|neurofilament subunit NF-L|neurofilament triplet L protein|neurofilament, light polypeptide 68kDa|neurofilament-light
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Interactome
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Pathway
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Disease
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