NELL1 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human NELL1 protein.
Immunogen
NELL1 (AAH69674.1, 1 a.a. ~ 810 a.a) full-length human protein.
Sequence
MPMDLILVVWFCVCTARTVVGFGMDPDLQMDIVTELDLVNTTLGVAQVSGMHNASKAFLFQDIEREIHAAPHVSEKLIQLFRNKSEFTILATVQQKPSTSGVILSIRELEHSYFELESSGLRDEIRYHYIHNGKPRTEALPYRMADGQWHKVALSVSASHLLLHVDCNRIYERVIDPPDTNLPPGINLWLGQRNQKHGLFKGIIQDGKIIFMPNGYITQCPNLNHTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDDFSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECALRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTACDCQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSPCTTCKCKNGRVCCSVDFECLQNN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NELL1 expression in transfected 293T cell line (H00004745-T01) by NELL1 MaxPab polyclonal antibody.
Lane 1: NELL1 transfected lysate(89.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Western Blot analysis of NELL1 recombinant protein (H00004745-P01) by NELL1 purified MaxPab mouse polyclonal antibody. -
Gene Info — NELL1
Entrez GeneID
4745GeneBank Accession#
BC069674.1Protein Accession#
AAH69674.1Gene Name
NELL1
Gene Alias
FLJ45906, IDH3GL, NRP1
Gene Description
NEL-like 1 (chicken)
Omim ID
602319Gene Ontology
HyperlinkGene Summary
This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
isocitrate dehydrogenase 3 (NAD+) gamma-like|nel-like 1|neural epidermal growth factor-like 1
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Interactome
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Disease
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Publication Reference
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Oligomerization-induced Conformational Change in the C-terminal Region of NELL1 Is Necessary for the Efficient Mediation of Murine MC3T3-E1 Cell Adhesion and Spreading.
Nakamura Y, Hasebe A, Takahashi K, Iijima M, Yoshimoto N, Maturana AD, Ting K, Kuroda S, Niimi T.
The Journal of Biological Chemistry 2014 Apr; 289(14):9781.
Application:WB-Tr, Human, IMR-32, 293-F cells.
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Efficient Production and Characterization of Recombinant Human NELL1 Protein in Human Embryonic Kidney 293-F Cells.
Hasebe A, Tashima H, Ide T, Iijima M, Yoshimoto N, Ting K, Kuroda S, Niimi T.
Molecular Biotechnology 2012 May; 51(1):58.
Application:WB-Re, Recombinant proteins.
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Oligomerization-induced Conformational Change in the C-terminal Region of NELL1 Is Necessary for the Efficient Mediation of Murine MC3T3-E1 Cell Adhesion and Spreading.
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