NEDD9 monoclonal antibody (M01), clone 1B4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NEDD9.
Immunogen
NEDD9 (NP_006394, 101 a.a. ~ 200 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PRDTIYQVPPSYQNQGIYQVPTGHGTQEQEVYQVPPSVQRSIGGTSGPHVGKKVITPVRTGHGYVYEYPSRYQKDVYDIPPSHTTQGVYDIPPSSAKGPV
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NEDD9 expression in transfected 293T cell line by NEDD9 monoclonal antibody (M01), clone 1B4.
Lane 1: NEDD9 transfected lysate(92.9 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to NEDD9 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — NEDD9
Entrez GeneID
4739GeneBank Accession#
NM_006403Protein Accession#
NP_006394Gene Name
NEDD9
Gene Alias
CAS-L, CAS2, CASL, CASS2, HEF1, dJ49G10.2, dJ761I2.1
Gene Description
neural precursor cell expressed, developmentally down-regulated 9
Omim ID
602265Gene Ontology
HyperlinkGene Summary
O
Other Designations
Cas scaffolding protein family member 2|Crk-associated substrate related|OTTHUMP00000016030|cas-like docking|dJ49G10.2 (Enhancer of Filamentation 1 (HEF1))|dJ761I2.1 (enhancer of filamentation (HEF1))|enhancer of filamentation 1
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Interactome
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Disease
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Publication Reference
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Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.
Li Y, Grupe A, Rowland C, Holmans P, Segurado R, Abraham R, Jones L, Catanese J, Ross D, Mayo K, Martinez M, Hollingworth P, Goate A, Cairns NJ, Racette BA, Perlmutter JS, O'Donovan MC, Morris JC, Brayne C, Rubinsztein DC, Lovestone S, Thal LJ, Owen MJ, W.
Human Molecular Genetics 2007 Dec; 17(5):759.
Application:IHC, Human, Brain from patients with Alzheimer’s and Parkinson’s disease.
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Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease.
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