NDP (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human NDP full-length ORF ( NP_000257.1, 1 a.a. - 133 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MRKHVLAASFSMLSLLVIMGDTDSKTDSSFIMDSDPRRCMRHHYVDSISHPLYKCSSKMVLLARCEGHCSQASRSEPLVSFSTVLKQPFRSSCHCCRPQTSKLKALRLRCSGGMRLTATYRYILSCHCEECNS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
41.4
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NDP
Entrez GeneID
4693GeneBank Accession#
NM_000266.1Protein Accession#
NP_000257.1Gene Name
NDP
Gene Alias
EVR2, FEVR, ND
Gene Description
Norrie disease (pseudoglioma)
Gene Ontology
HyperlinkGene Summary
This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway. The protein forms disulfide-linked oligomers in the extracellular matrix. Mutations in this gene result in Norrie disease and X-linked exudative vitreoretinopathy. [provided by RefSeq
Other Designations
OTTHUMP00000023168|norrin
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Interactome
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Disease
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