NCF2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human NCF2 partial ORF ( AAH01606, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAFTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (84); Rat (80)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NCF2
Entrez GeneID
4688GeneBank Accession#
BC001606Protein Accession#
AAH01606Gene Name
NCF2
Gene Alias
FLJ93058, NCF-2, NOXA2, P67-PHOX, P67PHOX
Gene Description
neutrophil cytosolic factor 2
Gene Ontology
HyperlinkGene Summary
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in two transcript variants that encode the same protein. [provided by RefSeq
Other Designations
67 kDa neutrophil oxidase factor|NADPH oxidase activator 2|OTTHUMP00000033269|OTTHUMP00000033270|chronic granulomatous disease, autosomal 2|neutrophil cytosol factor 2|neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2)
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Interactome
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Pathway
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Disease
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