NCF2 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human NCF2 protein.
Immunogen
NCF2 (AAH01606.1, 1 a.a. ~ 526 a.a) full-length human protein.
Sequence
MSLVEAISLWNEGVLAADKKDWKGALDAFSAVQDPHSRICFNIGCMYTILKNMTEAEKAFTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEALIQLRGNQLIDYKILGLQFKLFACEVLYNIAFMYAKKEEWKKAEEQLALATSMKSEPRHSKIDKAMECVWKQKLYEPVVIPVGRLFRPNERQVAQLAKKDYLGKATVVASVVDQDSFSGFAPLQPQAAEPPPRPKTPEIFRALEGEAHRVLFGFVPETKEELQVMPGNIVFVLKKGNDNWATVMFNGQKGLVPCNYLEPVELRIHPQQQPQEESSPQSDIPAPPSSKAPGRPQLSPGQKQKEEPKEVKLSVPMPYTLKVHYKYTVVMKTQPGLPYSQVRDMVSKKLELRLEQTKLSYRPRDSNELVPLSEDSMKDAWGQVKNYCLTLWCENTVGDQGFPDEPKESEKADANNQTTEPQLKKGSQVEALFSYEATQPEDLEFQEGDIILVLSKVNEEWLEGECKGKVGIFPKVFVEDCATTDLESTRREV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (85); Rat (73)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of NCF2 expression in transfected 293T cell line (H00004688-T01) by NCF2 MaxPab polyclonal antibody.
Lane 1: NCF2 transfected lysate(57.86 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to NCF2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — NCF2
Entrez GeneID
4688GeneBank Accession#
BC001606.1Protein Accession#
AAH01606.1Gene Name
NCF2
Gene Alias
FLJ93058, NCF-2, NOXA2, P67-PHOX, P67PHOX
Gene Description
neutrophil cytosolic factor 2
Gene Ontology
HyperlinkGene Summary
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in two transcript variants that encode the same protein. [provided by RefSeq
Other Designations
67 kDa neutrophil oxidase factor|NADPH oxidase activator 2|OTTHUMP00000033269|OTTHUMP00000033270|chronic granulomatous disease, autosomal 2|neutrophil cytosol factor 2|neutrophil cytosolic factor 2 (65kD, chronic granulomatous disease, autosomal 2)
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Interactome
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Pathway
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Disease
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Publication Reference
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MicroRNA-524 inhibits the progress of glioma via the direct targeting of NCF2.
Xu T, Yu W, Li Q, Li X, Shi Y, Cao B, Zhang Y, Wang S, Zhang Y, Wang T, Huang B.
American Journal of Translational Research 2019 Mar; 11(3):1605.
Application:WB-Tr, Human, U251, U87 cells.
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MicroRNA-524 inhibits the progress of glioma via the direct targeting of NCF2.
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