NBL1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
NBL1 transfected lysate.
Western Blot
Lane 1: NBL1 transfected lysate ( 19.91 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-NBL1 full-length
Host
Human
Theoretical MW (kDa)
19.3
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-NBL1 antibody (H00004681-D01P) by Western Blots.
SDS-PAGE Gel
NBL1 transfected lysate.
Western Blot
Lane 1: NBL1 transfected lysate ( 19.91 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — NBL1
Entrez GeneID
4681GeneBank Accession#
NM_005380Protein Accession#
NP_005371.1Gene Name
NBL1
Gene Alias
D1S1733E, DAN, DAND1, MGC8972, NB, NO3
Gene Description
neuroblastoma, suppression of tumorigenicity 1
Omim ID
600613Gene Ontology
HyperlinkGene Summary
This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
differential screening-selected gene aberrant in neuroblastoma|neuroblastoma candidate region, suppression of tumorigenicity 1|neuroblastoma suppressor of tumorigenicity 1
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