NAGLU monoclonal antibody (M02), clone 1B7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NAGLU.
Immunogen
NAGLU (NP_000254, 644 a.a. ~ 742 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
YQLTLWGPEGNILDYANKQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQFDKNVFQLEQAFVLSKQRYPSQPRGDTVDLAKKIFLKYYPGWVAGS
Host
Mouse
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (80); Rat (76)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
NAGLU monoclonal antibody (M02), clone 1B7. Western Blot analysis of NAGLU expression in NIH/3T3.Western Blot (Recombinant protein)
ELISA
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Gene Info — NAGLU
Entrez GeneID
4669GeneBank Accession#
NM_000263Protein Accession#
NP_000254Gene Name
NAGLU
Gene Alias
MPS-IIIB, MPS3B, NAG, UFHSD
Gene Description
N-acetylglucosaminidase, alpha-
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq
Other Designations
N-acetyl-alpha-glucosaminidase|alpha-N-acetylglucosaminidase
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Interactome
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Pathway
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