NAB2 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human NAB2 partial ORF ( NP_005958.1, 421 a.a. - 525 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
DGHLQAVGSCPRLTPPPADLPLALPAHGLWSRHILQQTLMDEGLRLARLVSHDRVGRLSPCVPAKPPLAEFEEGLLDRCPAPGPHPALVEGRRSSVKVEAEASRQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.29
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NAB2
Entrez GeneID
4665GeneBank Accession#
NM_005967Protein Accession#
NP_005958.1Gene Name
NAB2
Gene Alias
MADER, MGC75085
Gene Description
NGFI-A binding protein 2 (EGR1 binding protein 2)
Omim ID
602381Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
EGR1 binding protein 2|NGFI-A binding protein 2|melanoma-associated delayed early response protein
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Interactome
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Disease
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