NAB2 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96%); Rat (95%)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of NAB2 transfected lysate using rabbit polyclonal anti-NAB2 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-NAB2.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-NAB2 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-NAB2 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — NAB2
Entrez GeneID
4665Gene Name
NAB2
Gene Alias
MADER, MGC75085
Gene Description
NGFI-A binding protein 2 (EGR1 binding protein 2)
Omim ID
602381Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
EGR1 binding protein 2|NGFI-A binding protein 2|melanoma-associated delayed early response protein
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Interactome
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Disease
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