Western blot analysis of MYOG over-expressed 293 cell line, cotransfected with MYOG Validated Chimera RNAi ( Cat # H00004656-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MYOG monoclonal antibody (M01), clone 2B7 (Cat # H00004656-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle. [provided by RefSeq