MYOC DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human MYOC DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — MYOC
Entrez GeneID
4653GeneBank Accession#
NM_000261.1Protein Accession#
NP_000252.1Gene Name
MYOC
Gene Alias
GLC1A, GPOA, JOAG, JOAG1, TIGR, myocilin
Gene Description
myocilin, trabecular meshwork inducible glucocorticoid response
Gene Ontology
HyperlinkGene Summary
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq
Other Designations
OTTHUMP00000032681|mutated trabecular meshwork-induced glucocorticoid response protein|myocilin
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Interactome
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Disease
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