MYOC 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MYOC full-length
Host
Human
Theoretical MW (kDa)
57
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MYOC antibody (H00004653-D01P) by Western Blots.
SDS-PAGE Gel
MYOC transfected lysate.
Western Blot
Lane 1: MYOC transfected lysate ( 57.00 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MYOC
Entrez GeneID
4653GeneBank Accession#
NM_000261.1Protein Accession#
NP_000252.1Gene Name
MYOC
Gene Alias
GLC1A, GPOA, JOAG, JOAG1, TIGR, myocilin
Gene Description
myocilin, trabecular meshwork inducible glucocorticoid response
Gene Ontology
HyperlinkGene Summary
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq
Other Designations
OTTHUMP00000032681|mutated trabecular meshwork-induced glucocorticoid response protein|myocilin
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