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MYOC Validated Chimera RNAi

  • Catalog # : H00004653-R01V
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  • Specification
  • Product Description:
  • Homo sapiens myocilin, trabecular meshwork inducible glucocorticoid response (MYOC), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000261
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
  • Western blot analysis of MYOC over-expressed 293 cell line, cotransfected with MYOC Validated Chimera RNAi ( Cat # H00004653-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MYOC monoclonal antibody (M01), clone 4F8 (Cat # H00004653-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
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  • Application Image
  • RNAi Knockdown (Antibody validated)
  • RNAi Knockdown (Antibody validated)
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  • Gene Information
  • Entrez GeneID:
  • 4653
  • Gene Name:
  • MYOC
  • Gene Alias:
  • GLC1A,GPOA,JOAG,JOAG1,TIGR,myocilin
  • Gene Description:
  • myocilin, trabecular meshwork inducible glucocorticoid response
  • Gene Summary:
  • MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032681,mutated trabecular meshwork-induced glucocorticoid response protein,myocilin
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