MYOC monoclonal antibody (M02), clone 2B4

Catalog # H00004653-M02

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Size:100 ug
Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Transfected lysate)
Application

Western Blot (Transfected lysate)

Western Blot analysis of MYOC expression in transfected 293T cell line by MYOC monoclonal antibody (M02), clone 2B4.

Lane 1: MYOC transfected lysate(57 KDa).
Lane 2: Non-transfected lysate.

Sandwich ELISA (Recombinant protein)
Application

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged MYOC is approximately 0.3ng/ml as a capture antibody.

QC Test

Western Blot detection against Immunogen (81.18 KDa) .

  • Specification

    Product Description

    Mouse monoclonal antibody raised against a full-length recombinant MYOC.

    Immunogen

    MYOC (AAH29261, 1 a.a. ~ 504 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    Sequence

    MRFFCARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM

    Host

    Mouse

    Reactivity

    Human

    Isotype

    IgG2b Kappa

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Western Blot detection against Immunogen (81.18 KDa) .

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Transfected lysate)

    Western Blot analysis of MYOC expression in transfected 293T cell line by MYOC monoclonal antibody (M02), clone 2B4.

    Lane 1: MYOC transfected lysate(57 KDa).
    Lane 2: Non-transfected lysate.

    Western Blot (Recombinant protein)

    Sandwich ELISA (Recombinant protein)

    Detection limit for recombinant GST tagged MYOC is approximately 0.3ng/ml as a capture antibody.

    ELISA

  • Gene Info — MYOC

    Entrez GeneID

    4653

    GeneBank Accession#

    BC029261

    Protein Accession#

    AAH29261

    Gene Name

    MYOC

    Gene Alias

    GLC1A, GPOA, JOAG, JOAG1, TIGR, myocilin

    Gene Description

    myocilin, trabecular meshwork inducible glucocorticoid response

    Omim ID

    137750 601652

    Gene Ontology

    Hyperlink

    Gene Summary

    MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq

    Other Designations

    OTTHUMP00000032681|mutated trabecular meshwork-induced glucocorticoid response protein|myocilin

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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