MYOC rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MYOC peptide using ARM Technology.
Immunogen
A synthetic peptide of human MYOC is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MYOC peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MYOC
Entrez GeneID
4653GeneBank Accession#
MYOCGene Name
MYOC
Gene Alias
GLC1A, GPOA, JOAG, JOAG1, TIGR, myocilin
Gene Description
myocilin, trabecular meshwork inducible glucocorticoid response
Gene Ontology
HyperlinkGene Summary
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq
Other Designations
OTTHUMP00000032681|mutated trabecular meshwork-induced glucocorticoid response protein|myocilin
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