MYL3 monoclonal antibody (M12), clone 4C2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant MYL3.
Immunogen
MYL3 (AAH09790, 1 a.a. ~ 195 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (47.19 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MYL3 expression in transfected 293T cell line by MYL3 monoclonal antibody (M12), clone 4C2.
Lane 1: MYL3 transfected lysate(21.9 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MYL3 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — MYL3
Entrez GeneID
4634GeneBank Accession#
BC009790Protein Accession#
AAH09790Gene Name
MYL3
Gene Alias
CMH8, MLC1SB, MLC1V, VLC1
Gene Description
myosin, light chain 3, alkali; ventricular, skeletal, slow
Gene Ontology
HyperlinkGene Summary
MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq
Other Designations
OTTHUMP00000165922|myosin, light polypeptide 3, alkali; ventricular, skeletal, slow|slow skeletal ventricular myosin alkali light chain 3
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Interactome
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Pathway
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Disease
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