MXI1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
MXI1 transfected lysate.
Western Blot
Lane 1: MXI1 transfected lysate ( 20.13 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MXI1 full-length
Host
Human
Theoretical MW (kDa)
20.13
Interspecies Antigen Sequence
Mouse (91); Rat (94)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MXI1 antibody (H00004601-B01) by Western Blots.
SDS-PAGE Gel
MXI1 transfected lysate.
Western Blot
Lane 1: MXI1 transfected lysate ( 20.13 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MXI1
Entrez GeneID
4601GeneBank Accession#
BC035128Protein Accession#
AAH12907Gene Name
MXI1
Gene Alias
MAD2, MGC43220, MXD2, MXI, bHLHc11
Gene Description
MAX interactor 1
Gene Ontology
HyperlinkGene Summary
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq
Other Designations
MAX dimerization protein 2|MAX interacting protein 1|MAX-interacting protein 1|Max-related transcription factor|OTTHUMP00000020467|OTTHUMP00000020468|OTTHUMP00000020469
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Interactome
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Disease
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