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Last updated: 2016/12/4
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MXI1 monoclonal antibody (M11), clone 1B10

  • Catalog # : H00004601-M11
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a full-length recombinant MXI1.
  • Immunogen:
  • MXI1 (AAH12907, 1 a.a. ~ 182 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2a Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00004601-M11
    Western Blot detection against Immunogen (45.76 KDa) .
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence of monoclonal antibody to MXI1 on U-2 OS cell. [antibody concentration 10 ug/ml]
  • PDF DownloadProtocol Download
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Detection limit for recombinant GST tagged MXI1 is 0.03 ng/ml as a capture antibody.
  • PDF DownloadProtocol Download
  • ELISA
  • Immunofluorescence (Circulating Tumor Cell)
  • Application Image
  • Western Blot (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • enlarge
  • ELISA
  • Immunofluorescence (Circulating Tumor Cell)
  • Gene Information
  • Entrez GeneID:
  • 4601
  • Gene Name:
  • MXI1
  • Gene Alias:
  • MAD2,MGC43220,MXD2,MXI,bHLHc11
  • Gene Description:
  • MAX interactor 1
  • Gene Summary:
  • Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq
  • Other Designations:
  • MAX dimerization protein 2,MAX interacting protein 1,MAX-interacting protein 1,Max-related transcription factor,OTTHUMP00000020467,OTTHUMP00000020468,OTTHUMP00000020469
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