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Last updated: 2016/10/23
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MXI1 MaxPab mouse polyclonal antibody (B01)MaxPab

  • Catalog # : H00004601-B01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human MXI1 protein.
  • Immunogen:
  • MXI1 (AAH12907, 1 a.a. ~ 182 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of MXI1 expression in transfected 293T cell line (H00004601-T03) by MXI1 MaxPab polyclonal antibody.

    Lane 1: MXI1 transfected lysate(20.13 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 4601
  • Gene Name:
  • MXI1
  • Gene Alias:
  • MAD2,MGC43220,MXD2,MXI,bHLHc11
  • Gene Description:
  • MAX interactor 1
  • Gene Summary:
  • Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq
  • Other Designations:
  • MAX dimerization protein 2,MAX interacting protein 1,MAX-interacting protein 1,Max-related transcription factor,OTTHUMP00000020467,OTTHUMP00000020468,OTTHUMP00000020469
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