Transient overexpression cell lysate was tested with Anti-MX2 antibody (H00004600-B01) by Western Blots. SDS-PAGE Gel MX2 transfected lysate. Western Blot Lane 1: MX2 transfected lysate ( 78.76 KDa) Lane 2: Non-transfected lysate.
Storage Buffer:
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction:
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq
Other Designations:
interferon-regulated resistance GTP-binding protein MXB,myxovirus resistance protein 2,second interferon-induced protein p78