MX1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MX1 protein.
Immunogen
MX1 (NP_002453.1, 1 a.a. ~ 662 a.a) full-length human protein.
Sequence
MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRGALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLIIQFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQFPG
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
MX1 MaxPab rabbit polyclonal antibody. Western Blot analysis of MX1 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of MX1 expression in transfected 293T cell line (H00004599-T02) by MX1 MaxPab polyclonal antibody.
Lane 1: MX1 transfected lysate(75.50 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to MX1 on HeLa cell. [antibody concentration 30 ug/ml] -
Gene Info — MX1
Entrez GeneID
4599GeneBank Accession#
NM_002462Protein Accession#
NP_002453.1Gene Name
MX1
Gene Alias
IFI-78K, IFI78, MX, MxA
Gene Description
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
Omim ID
147150Gene Ontology
HyperlinkGene Summary
In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
interferon inducible protein p78|interferon-regulated resistance GTP-binding protein|myxovirus resistance protein 1
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Interactome
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Disease
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Publication Reference
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Subcellular localization of MxB determines its antiviral potential against influenza A virus.
Fiona Steiner, Jovan Pavlovic.
Journal of Virology 2020 Oct; 94(22):e00125.
Application:WB-Tr, Human, HEK 293T cells.
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Subcellular localization of MxB determines its antiviral potential against influenza A virus.
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