MX1 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MX1 protein.
Immunogen
MX1 (NP_002453.1, 1 a.a. ~ 662 a.a) full-length human protein.
Sequence
MVVSEVDIAKADPAAASHPLLLNGDATVAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSYQDYEIEISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKGYMIVKCRGQQEIQDQLSLSEALQREKIFFENHPYFRDLLEEGKATVPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPEDENEKMFFLIDKINAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKILSRKIQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIKNFEEFFNLHRTAKSKIEDIRAEQEREGEKLIRLHFQMEQIVYCQDQVYRGALQKVREKELEEEKKKKSWDFGAFQSSSATDSSMEEIFQHLMAYHQEASKRISSHIPLIIQFFMLQTYGQQLQKAMLQLLQDKDTYSWLLKERSDTSDKRKFLKERLARLTQARRRLAQFPG
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MX1 MaxPab polyclonal antibody. Western Blot analysis of MX1 expression in Jurkat.Western Blot (Transfected lysate)
Western Blot analysis of MX1 expression in transfected 293T cell line (H00004599-T01) by MX1 MaxPab polyclonal antibody.
Lane 1: MX1 transfected lysate(72.82 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MX1
Entrez GeneID
4599GeneBank Accession#
NM_002462Protein Accession#
NP_002453.1Gene Name
MX1
Gene Alias
IFI-78K, IFI78, MX, MxA
Gene Description
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
Omim ID
147150Gene Ontology
HyperlinkGene Summary
In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
interferon inducible protein p78|interferon-regulated resistance GTP-binding protein|myxovirus resistance protein 1
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Interactome
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Disease
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Publication Reference
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Genomic Instability Is Defined by Specific Tumor Microenvironment in Ovarian Cancer: A Subgroup Analysis of AGO OVAR 12 Trial.
Jean-David Fumet, Emilie Lardenois, Isabelle Ray-Coquard, Philipp Harter, Florence Joly, Ulrich Canzler, Caroline Truntzer, Olivier Tredan, Clemens Liebrich, Alain Lortholary, Daniel Pissaloux, Alexandra Leary, Jacobus Pfisterer, Alexandre Eeckhoutte, Felix Hilpert, Michel Fabbro, Christophe Caux, Jérôme Alexandre, Aurélie Houlier, Jalid Sehouli, Emilie Sohier, Rainer Kimmig, Bertrand Dubois, Dominique Spaeth, Isabelle Treilleux, Jean-Sébastien Frenel, Uwe Herwig, Olivia Le Saux, Nathalie Bendri
Cancers 2022 Feb; 14(5):1189.
Application:IHC, Human, Human high grade serous ovarian carcinoma.
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Vitamin-D: An innate antiviral agent suppressing Hepatitis C virus in human hepatocytes.
Gal-Tanamy M, Bachmetov L, Ravid A, Koren R, Erman A, Tur-Kaspa R, Zemel R.
Hepatology 2011 Nov; 54(5):1570.
Application:WB, Human, HepG2, Huh7.5 cells.
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Genomic Instability Is Defined by Specific Tumor Microenvironment in Ovarian Cancer: A Subgroup Analysis of AGO OVAR 12 Trial.
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